Reference Articles

The Treatment of Cancer on the basis of Ayurvedic Principles and Medicines

ZACHARIA JACOB,
Director,
Athulya Ayurvedic Medical Research Centre (AAMRC),
Mundikkalthazham, Kottamparamba P.O.
Medical College - Karanthur Road,
Calicut - 673008, Kerala, India,
Tel: 0495-2358016, 2356391
E-mail : ayurvediccancertherapy@rediffmail.com

Ayurvedic System of medicine and practice have been regarded as one of the safest alternative therapies for cure of diseases. The best alternative advantages of this therapy are (a) the resource materials are natural (b) Safe and easy administration and (c) medicines do not leave side effects on patients.

According to Ayurveda, the disease have definite etiology, prognosis and treatment. The medicines recorded in the texts (samhitas) were formulated and efficacies were tested. The treatment protocols and knowledge were transferred from generation to generations. Details of surgery were recorded in the Susrutha Samhitha. This science flourished very well till the beginning of colonial rule in India.
Arbhudha (Cancer)
Cancer is known as arbhudha in Ayurveda. There are six types of arbhudha affecting vata, pitta, kapha, rekhta, mamsa and medasu. The epidemiology and prognosis have already been explained before (www.ayurvediccancertherapy.com ). However, for the interest of the august gathering few important things are mentioned here.

Bhukthaai: Paryooshitha thyushna ruksha vidhahibi:
Jhinhama sayyavi chestabhi sthy sthy shcha srukku pradhooshanai:
Dhusta thwangh mamsa medhosthi snava srukhandarasrya:
Yasso pho bhaheer andharava mahamoolo maharuja:
Vruthassya dhayadho yo va smritha: shoda sa vidhradhi:
Dhoshai pradhak samudhi thai shonithena kshathena cha
(Ashtangahridhayam)


The meaning of the above verses could be explained as follows:
Consumption of old rotten foods, dried and over spicy foods and food that create gastric burning, unnatural postures of laying and working, unethical deeds that affects constitution and development of the body and exposure to toxins affecting the functions of thwack, rekhta, mamsa, medasu, asthi, khandhara and snanu are the reasons for Arbhudha .The humors thus formed are expressed as spherical or oblong oedema (sopha) as a defensive mechanism of the body either externally or internally. These abnormal structures are classified as vata, pitta, kapha, sannipatha, kshatha, rekhta and vidhradhi, on the basis of prominence of dhoshas.

Gathra pradhese kwachi deva dosha:
Sammoorchitha mamsa masruck Pradhooshya
Vrutham sthiram mandharucham mahanth-
Manalpa moolam chiravrudhi paakam
Kuruvanthi mansoch chrayamathyaghatham
Thadharbudha Sasthra vid ho vadanthi
Vathena pithena kaphena chapi
Rakhthena mamsena cha- medasa cha
Thajjayathe thasya cha lakshanani
Grandhe ssa manani thadha Bhavanthi
(Sarvarooga Chikilsa Rathnam)


The predisposing factors of Arbhudha cause to create impure vata, pitta, kapha, Mamsa and Medhasu. The impure humors thus formed are either systemic or exogenous. They are primarily benign and metamorphosed to tumerous, cyst or plaque like structures. As the impure humors increase in quantity, the abnormally formed structures become malignant.

Symptoms and prognosis of Rekhtharbudha

Dhosha: pradhushto rudhiram sirhascha
Samkoojjya sampindhya thatha sthwa pakam
Samsrava munnahyathi mamsapindhham
Mamsankoorairachitha masu virdheem
Karothyajasram rhudhira pravruthi
Ma sadhyajetha dhrudhira Imakanthu
Rhekhthakshayaopdrava peedithathwal
Pandhoorbhavedharbhudha peedhithasthu


In Rekhtharbudha the impure humors of vata, pitta or kapha engulf or amalgamate to form tumors with many raised heads. These tumors grow suddenly in size and ooze out blood and serum. According to acharyas, this type Rekhtharbudha patients are anaemic and untreatable.

Epidemiology and symptoms of Mamsarbhudha


Let us examine how Rekhtharbudha is characterized.
Mushti paraharaadhi bhirardhi themgay
Mamsa pradhushtam jhavayadhi sopam
Avethanam snikdtha manannya varna
Ma paka masoshmapama mapra chalyam
Pradhushta mamsa ssasrya narassya ghadha
Medhalbha ve nmam sa parayannsya
Mamsarbhudhanandhwa thadha sadhya muktham
Sardhaye shwa pee mani thu varjja yecha


First fighting and accidents cause trauma and oedema. The swollen mamsa (the traumatic injuries) initially is painless, non-ulcerous with normal skin colour and texture and oleaginous. These structures gradually become stone like hardened mass. Mamsarbhudha occurs in those who eat excess quantities of meat and to whose mamsa filled with humors. Acharyas also mentioned that this type of disease is untreatable.

Recurrence of Arbhudha

Recurrences of Arbhudha happens in the secondary phase of the disease.

Yajjaya thyel ghalu poorvajhathae
Knajyam thadhyarbudha marbhudha kjnay
Yal dhwandhwa jhatham yugpath kramadhwa
Dhwirarbudham thacha bhavadha sadhyam
(Sushrutham)

Recurrence of malignant tumors at the same point of earlier tumors is called Adhyarbhudham and to those adnexa is called dhwirarbhudham.

Hypothesis

A hypothesishas been reported earlier (Jacob 1998) regarding epidemiology and prognosis of arbhudha (cancer). Arbhudha can be defined as a deficiency syndrome expressed as an allergic manifestation wherein certain predisposing complaints of impure vata, pitta, kapha, Mamsa and Medhasu develop primarily benign and painless spherical or deep rooted plaques. This gradually spread and form excruciating pain.

The above hypothesis is expressed mathematically as follows:

BMA (Balanced Metabolic Activities) Normal Stage
IBMA (Imbalanced Metabolic Activities) Diseased stage
i.e. IBMA 1/BMA Diseased stage
i.e. :IBMA=k/BMA
where k is the balancing constant
Therefore k is a function of IBMA

k/BMA………………..primary stage
k’/BMA……………….secondary stage
k” /BMA……………….advanced stage

The progress of the disease can be expressed as follows:

To arrive at the above hypothesis mainly four aspects, viz., balanced metabolic activities(BMA), imbalanced Metabolic activities(IBMA), Maladhosha of Thridosha and dhadhu and presence of factor k have been considered. Normal individuals have sufficiency in all factors responsible for non-allergencity to carcinogenic agents and the maladhosha are cleared from the system in normal fashion. While in Cancer patients who are insufficient in certain factors and possessing factor k responsible for alleginicity to various agents and the maladhoshas are not cleared properly. In primary stage patients who are exposed to allergic agents, thebody system acts defensivelyresulting in elevated body temperature, gas, high density fluids (neoplasmic fluids, phlegm, or mucosal fluids, so that the maladhosha could be excreted through sweat, urine or stool. All the cancer patients are allergic to any of the chemical based drugs like sulphadrugs, antibiotics, exposure to chemicals, radiations or microbial agents in nature and eatables like fish, meat, milk and so on. But, when this physiological abnormality of allergencity is not effectively controlled, the intensity of the maladhosha production and retention would be multiplied in many folds and thereby affecting the other vital metabolic activities to a stand still. The maladhosha are excreted partially in cancer patients. The high density neoplasmic fluids rich in protein and salts are of no use to the system and cannot be translocated fully to the kidneys for filteration. In primary stage patients, some degree of filteration might be possible but it progressively ends with calculi formations. Similar observations can also be made with in the functions of galol bladder, pancreas, spleen etc.

In certain other instance the maladhoshas while the translocation gets localized or circulated in the system through blood or lymph and develop regional lymph nodes or vessel nodes. As the situation progresses more number of similar nodes are thus formed and they gradually develop ulceroproliferative lesions with severs pain. In otheinstances, obnoxious gas, phlegm, or mucus secretion are blocked their passage in regions of injury and trauma affected aspects, develop severe pain and sufferings to the patient. Thus depending on the intensity of maladhosha (deficiencies caused by impurities discharges on account of Thridhosha and Dhadhudhoshas) retention and excretion of maladhosha the prognosis can be classified as primary, secondary and advanced stages. The expression of factor k can be delayed by giving simultaneous samana chikilsa proper anti-allergic medication and medicinesfor balancing Thridhosha and Dhadhus. Therefore the above protocol has to be repeated periodically as and when requiredin patients with deficiency factor k. This tells the importance of Ayurveda in the treatment of cancer. Therefore a general protocol can be advocated which may have samana Chikilsa as the primary step. As a next step a clever Ayurvedic Physician would therefore diagnose the prime dhoshas (either of Thridhosha and Dhadhudhoshas) and effectively treat patients with sodhana chikilsa and hence it would be possible to cure most of the cancer patients.

Treatment at AAMRC

All Cancer patients suffer from dhadhukshayam (deterioration of dhadhu). This create a state of ajeerna and ama (indigestion and toxicity) in the patients. Therefore the physician has to concentrate on dhadhukshayam, detoxification and selective destruction of cancer cells without affecting the normal cells.

Table I gives general strategy which is used in cancer therapy.
Table I : General Strategies and their significance in cancer therapy

Steps  Significants 
Virechana  Bowl movement helps digestion and detoxification 
Biochip therapy  Detoxification 
Administration of Anti-Cancer medicines  Selective destruction of cancer cells, no side effects 
Dhadhu pushti and maintenance  Rejuvenation of organs and sound health 

We have found that certain combinations of medicines have excellent anti-cancer properties. For example, SJ-29 (Spl. Drop concentrate) which selectively stops multiplication of cancer cells. Here, the protein synthesis is hindered and further multiplication is not possible.

         The ‘ama’ state (the toxic state due to indigestion, consumption of wrong medicines, food or any agent etc.) could be neutralized by consumption of medicines like villuwadi(lehyam, tablet, decoction). Another method is bio chip therapy. In which chips are attached superficially on legs after a very minute cut with a sterilized blade. The chips in contact with blood neutralizes the toxins and excreted with the help of suitable diuretics. Virechana is another method by which the alimentary systems is cleaned with medicines.

         Virechana or vasti are performed according to body strength and intensity of the disease. Daily boel movement is required for effective therapy. Virechana could be done once initially and if required could be repeated every 8 or 15 days. Mostly a suitable laxative in minimum dose daily would help to solve the problem of constipation. Once the bowl movement start functioning, perfectly, use of laxative could be stopped. Medical attention is highly required during Virechana. It must be started in the empty stomach in the morning. No solid food for the whole day is advised. For effective evacuation of stool the patient should drink little hot water or rice or wheat porridge water with out salt. If the evacuation occurs more than 4 or 5 times it could be stopped by giving (a) porridge with salt(b) black tea with lemon or (c) yogurt.
          Medicines according to the prescription could be administered in the afternoon. It is not advisable to take shower after Virechana.

Nasyam:- is performed mostly during the morning hours, using Anuthylam or any suitable oil or swarasm of choice, depending on the need.
Oil Application :- Karpooradi oil application is done during the morning hours followed by washing with hot water after one hour.
Lepam:- A special lepam is formulated at AAMRC. This helps to remove toxins from the skin. Softening of mussels, better functioning of nervous system and to some extend remove general oedema.

Detoxification :- is done in two ways. If the ama is very vigorous, a preparation made of tablets of villuwadi, tulsi and honey are given to patients two or three times daily. This preparation also helps to stop nausea and vomiting in most of the pitta affected cases. Depending on the severity of pitta aggravations Villuwadi lehyam, villuwadi decoction are also administered.

         Another important detoxification method is biochip therapy. This techniques is used traditionally for cure of snake or insect bitten cases. This technique is adopted in for the cancer patients for removal of toxins, edema and inflammation and most importantly the excruciating pain. The chips are manufactured in traditional way. Here, a number of medicines are processed and molded. These chips could be used any numberof times after purification with milk. The exact working of bio chip on human body is unknown today. It is presumed that the complex molecules that are broken down to simpler ones and excreted through orine. Pathya has to be observed during biochip treatment.
They are:

1. One should follow vegetarianism.
2. No oil or fat consumption and no external application at the site of biochips.
3. Avoid spicy food, fast foods.
4. Reattach, milk purified biochips every 24 hours.



General Medicines used in cancer therapy


        Apart from Spl. Drop Concentrate, Varanadhi kashayam, parthathyarishtom, Punarnnavadi Kashayam, punarnnavasavam, Nisakadakadi kashayam, Lodhrasavam, Thikthakagritham, Sankbhasmam, Mahishadravaka, Balarishtom, Kudajarishtom, Draksharishtom, Chiruvilluwadi kashayam, Aswagandharishtom, Saraswatharishtom,, Tab. Kaisoragulgulu, Villuwadi, Rhumagia, Arshonyt, Gaytarine, Mandooravadakam, Sedubandham, Ponkarathi, Karthavattu, Capsules Neerjet, Calcurosin, Kachoorathi, Kamilari, Jeevanthyadi yamakam, Ksheerabala, Oint Artec, Karpoorathi thylam.

Medicines developed at AAMRC

Ksheerabaladhi Lepam, Nisathylam, Emelia lepam Danyamishritham, Soolasavam, Anuthylam (G), Spl. Enna, Mimosa Decoction, Burn oil, Ayisha Powder, Ekathi kashayam, leucoderma lepam.
Pathya:- The diet is very important while on treatment. Vegetarian food which are easy to digest must be used. Acid and gas forming foods must be avoided. Vegetable soups are good. Some items like potato, tomato, pineapple and certain , pulses are not good for their stomach. Saindhavu (Induppu) mixed with common salt could be used in diet. To some patients cow’s milk, grapes are allergic and must be avoided. Over proteinaceous and over fatty food must avoided. No animal proteins must be used. It has been observed that a small piece of ginger mixed with little salt before food intake is good for digestion, as well as for appetite in cancer patients. All spices are good except for green or red chillies.

Medication during convalescence

         All medicines prescribed in the diseased stage are not required in this stage. During recovery stages only spl. Drop concentrate has to be maintained in lower minimum dose. All vital organs start dysfunctioning in the beginning of the disease. As the patient recoup does of all other supportive medicines also could be gradually reduced.

Invention of Spl. Drop concentrate

        The invention of Spl. Drop concentrate (SJ-29) was quite accidental. Its anti-cancer activity against human cells lines (WM 902 B WM – 1341-D WM- 852) were noticed in 1993. Thereafter many repeated testings with many other melanoma cells lines were also done. The results were excellent and then the active chemical principle was found out. This medicine is now under patent processing.
         The plant extract dissolved in DMSO at various concentrations were used for testing. It was inhibitory even at 0.1 u/ml and almost complete inhibition was noticed with 2.5u/ml. Biochemically speaking, the thymidine synthesis for the multiplication of cancer cells are inhibited by SJ – 29. So, no further growth and multiplication is not possible. The beauty of SJ – 29 is that in human patients it acts selectively only on cancer cells. It is very safe and has absolutely no side effects on patients. Medicines prepared with SJ-29 are being used for many ailments, traditionally.

Preparation and administration of Spl. Drop concentrate

      Preparation SJ –29 produced in drops, tablets, syrups and ointment. Spl. Drop concentrate prepared is easily administered. For want of machinery and associated facilities, tablets and syrups are not prepared for the time being. The time taken for the extraction and further processing takes one week, in home scale.
    The optimum dose of Spl.Drops given to patients was approximately 100u/mg. each three times daily. Spl. Ointment prepared could be mixed with ksheerabala and other additives like clove oil, ointments for getting the desired results.

Results

The Spl. Drop concentrate has become the medicine of choice for cancer treatment to many patients, all over the world. Supplimentary medicines are inevitable for easy recovery. All the vital organs start dysfunctioning from the onset of the disease. So, revitalization of all organs are to be done simultaneously with the supplementary medicines.
       There is a wrong notion that Panchakarma procedure are good enough to remove all dhoshas from the body. In cancer patients, Panchakarma is not practicable. The neoplasmic fluids deposited in different parts of the body has higher density and cannot be easily filtered through kidneys. The existing Panchakarma procedures are not good enough to remove neoplasmic fluids. The high density neoplasmic fluid has to be broken with suitable agents like Induppu(saindhava), specific diuretics, special lepam application (external) and hot water bath. Patients with ascitis, pleural effusion etc. suffer finally with renal dysfunction and whole body oedema.

Success Rate

At AAMRC, we entertain all types of cancer patients. They are treated as inpatients or out patients. We recommended surgical intervention to patients as and when required. And we don’t recommend chemotherapy and radiation therapy. Cent percent success rate is possible in patients who have not received any other types of treatment like chemotherapy(CT) and radiation therapy(RT) (for e.g. Squamous Cell Carcinoma and adenocarcinoma patients). For other types of cancers which affect the ovary, prostrate etc and who received CT and RT earlier, the after effects have to be nullified and anticancer treatment have to be performed simultaneously. There is another category where the patients go for surgical interventions alsewhere and further anticancer treatment are carried out at AAMRC. The success rate in advanced stage is more than 50%. We are proud to say that many such cases have recovered miraculously from cancer.

         This medicine can also be taken as a prophylactic agent and many are being used now a days. The biggest advantage is that it has no side effects.