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Home Report of a new protocol for ovarian cancer treatment

ZACHARIA JACOB,
Director,
Athulya Ayurvedic Medical Research Centre (AAMRC),
Mundikkalthazham, Kottamparamba P.O.,
Medical College - Karanthur Road,
Calicut - 673008, Kerala, India,
Tel: 0495-2358016, 2356391
E-mail: ayurvediccancertherapy@rediffmail.com

In continuation to the earlier talk it was found pertinent to share the author’s experience with a new protocol in treating ovarian cancer patients with metastasis. As you all know, ovarian cancer is a malignant neoplasmic disease of the ovary, occurring most frequently in women between 40 and 60 years of age and occasionally in young women. It is rarely detected in the primary stages and mostly far advanced when diagnosed. Usually quoted risk factors are infertility, null parity or low parity, delayed child bearing, repeated abortions, endometriosis, exposure to chemical carcinogens and radiations, hormonal imbalance, etc. After and insidual start, the tumor may become evident as a palpable abdominal or pelvic mass accompanied by irregular or excessive menses or post menopausal bleeding. In stage III and IV, patients may have ascitis, pedal oedema, abdominal pain and swelling, discomfort, abnormal vaginal bleeding, weight loss, dysuria, constipation etc. Most ovarian carcinomas are papillary or serous. In many cases, the disease spreads over the surfact of peritoneum and also lymphatic vessels under the diaphragm and par-aortic nodes.

Table I to IV give and account of the details of two reference of ovarian carcinoma patients who took treatment from AAMRC.

The first reference case, Mrs. Jasmin was married at the age of 18 years and till at the age of 22 years she did not have any issues. The gynecologist did not find any abnormalities with the patient. In Nov. ’01, for fertility purpose, one week hormone therapy was advised. Consequently this developed uneasiness and discomfort to the patient. The ultra sonogram taken showed ovarian tumor in both ovaries. Histopathologically, the left serous type tumor had border line malignancy and the right one non-malignant. Immediate left oophrectomy was performed in Nov. ’01, itself and followed by some injections (details not available) monthly for five months. After a gap of six months, there was recurrence of the earlier complaints, discomfort and lower abdominal pain. The ultra sonogram showed an increased size of right ovary (5.8 x 5.1 cms). Later, when the patient consulted AAMRC the size of the tumor was 7.2 x 5 cms.

On examination at AAMRC, the patient had complaints of daily fever in the afternoons, no appetite for food, irregular menstrual cycle, pain at umbilicus aspect and psychological depression (Aug ’03). The patient was treated conservatively starting with virechana. The fever was controlled with Nimbadi kashayam and Tab. Sudarsanam for 10 days. Other medicines given were Vardhasavam + Tab. Kaisoragulgulu, Ndhrasavam, Calcurosine, Thikthakagritham and Sankbhasmam, Amruthachoornam in honey, Tab. Sivagulika in barley watem sukumaram kashayam + Aswagandharishtom + saraswatharishtom + T. Chabdraprabha anb Indukantham kashayam in milk. A decoction made of ginger + cardimum + garlic in honey increased appetite.

The SJ – 29 vaginal drops were inserted to the vagina after cleaning with hexidine solutions, two times daily. After 16 days of application there was abnormal per-vaginal bleeding for 3days.

The ultra sonogram taken in Jan ’04 indicated non-malignancy of the tumor because of the following reasons. 1. CA 125 readings reduced to almost normalcy (777.49 u/ml to 43.49 u/ml) 2. Ovarian internal nodule and wall thickness less than one cm. 3. No free fluid in abdomen and pelvis 4. No vascularity with in the nodule.

Let us examine the details of treatment of reference case number 2, Mrs. Sarala, (Table III &IV) It was diagnosed to have ovarian cyst. (5cms) in 1999.

She had vasectomy in 1976. subsequently, the patient had complaints of myofascial pain syndrome, lower abdominal pain, backache, oedema, uncontrolled urination, nausea, hyperacidity, insomnia, psychological depression, etc.

During AAMRC admission and treatment (Jan 99 to March 2000) the patient had SJ-29 vaginal insertion, and other conservative medicines like utrodap, Arshonyt, Rhue oil, sathavarigulam, Thikthakagritham + Sankbhasmam and chiruvilluwathi + Hudabhugathy. The patient also had antifungal medicines containing clotrimazole during the treatment.

In Nov ’99 when the ultra sonogram done it was found that the size of the cyst reduced to almost nil size. Hence no oophrectomy was done. Then patient gradually become normal in physique and spirit.

Discussion

While treating the first reference case, daily counseling was given to make the patient mentally fit. In other words, the patient was treated both mentally and physically. The patient was longing to become a mother, therefore only the malignant oophrectomy was performed. Earlier, the hormone therapy might have triggered the formation of ovarian cyst. When the physician advised for right oophretomy the patient became more mentally depressed and lost hopes even for survival. In this context, the SJ-29 drops vaginal insertion and supplementary medication destroyed the malignancy and gave ray of hopes and survival and aspiration to become a mother. The ultra sonogram taken after six months of treatment revealed that the right ovarian cyst was no longer malignant because 1) Uterus has normal size and echo texture 2) The internal wall thickness of the nodule was less than one cm. 3) No free fluid in abdomen and pelvis (on comparison with earlier scanning report of diseased stage). 4) Non-vascularity of the nodule and 5) Decreased CA values (almost normal) 77.49 to 43.49/ u/ml.

Looking at the potentials, it is proposed to refine the technique of vaginal insertion of SJ-29 drops and ‘ultra vasti’so that the ovarian cancer formation could be effectively controlled. The results of the treatment in reference case No.1 thus could be used as a lead in the day to come for concerted research and application.

The reference case number 2 Mrs. Sarala is and industrialist, housewife and a mother of three children. Her case history began with post vasectomy period when she had accidental fall and profused per vaginal bleeding and then immediate hysterectomy (performed in 1976). Since then the patient was suffering from myofascial pain syndrome, backache, nausea, acidity, depressive disorders, uncontrolled urination, etc. This long period of chronic sufferings and medication (1976 – 99) put the patient in lot of side effects and mental agony. The mental agony and sufferings were multiplied further when she was reported to have ovarian cyst in 1999. the SJ-29 drops insertion and conservative biochip therapy and medicated lepam and bath relieved her from all the complaints. Today she is a cheerful person, although she has minor complaints of occasional abdominal pain, acidity and indigestion. Oophrectomy was not performed in her so far, as the ovaries are intact and do not pause any health problems. This reference case and treatment results with SJ-29 drops insertion reiterate the fact that it is a potential anticancer medicine.

Table 1:Details of the reference case No.1

NameJasmin Age: 22ys.
Marital statusMarried and no issues
DiagnosisOvarian tumor
Treatment doneHormone therapy for one week (Nov ’01) Oophrectomy (Lt.) (Nov. ’01)
RecurrenceRt. Ovary cystic mass (5.8 x 5.1 cm)(April ’02)


Table II. Treatment at AAMRC and results

Date of admission4th Aug ‘03
Date of discharge18th Aug ‘03
Complaints fever, irregular menstrual cycle, no appetite, 
Psychological depression
TreatmentVaginal insertion of SJ-29 drops.
Conservative medication
Biochip therapy
Medicated lepam and bath
Results (USG) non-malignant cyst.


Table III: Details of the reference case No.2

NameSarala V.T Age: 42 ys.
Marital statusMarried and with 3 children
DiagnosisOvarian cyst (5cm) in 1999
Earlier historyVasectomy (1976)
Accidental fall and p/v bleeding (1976)
Abdominal hysterectomy (1976)
Complaints of myofasical pain syndrome, backache,
nausea, acidity, depressive disorders,
uncontrolled urination.


Table IV Treatment at AAMRC

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